Mouth and tongue cancer are included in the category of oral cancer. The skin lining the mouth and gums, beneath the tongue, at the base of the tongue, and in the region of the throat towards the rear of the mouth, oral malignancies can grow in tongue cancer. About 53,000 new cases of oral cancer, or 3% of all malignancies diagnosed each year in the United States, are oral cancer. More than twice as many men as women are affected by oral cancer, which most frequently affects adults over the age of 40. The lining of the lips, mouth can develop oral cancer which eventually becomes ulcer. Many oral cancer are linked to tobacco use, alcohol consumption (or both), and human papilloma virus infection (HPV).